INTENDED USE

Canine parvovirus (CPV), a nonenveloped single-stranded DNA (ssDNA) virus (family Parvoviridae, genus Protoparvovirus), is a highly successful pathogen that has sustained pandemic circulation in dogs for more than 40 years. Canine parvoviruses are in the form of CPV-1 and CPV-2. Most dogs of CPV-1 infection are asymptomatic. CPV-2 causes serious gastrointestinal and respiratory disease and has variants of CPV-2a, CPV-2b, and CPV-2c.

SUMMARY

CPV enters through the mouth from the ground or floor and its incubation period is three to seven days before dogs appear symptoms. CPV infected dogs appear lethargy, loss of appetite, abdominal bloating and pain, fever, or low body temperature (hypothermia), vomiting, and severe, often bloody, diarrhea.

PRINCIPLE

The CPV Ag Test Kit is a lateral flow chromatographic immunoassay for the qualitative detection of CPV antigens in canine feces. This kit shows two letters which are the test (T) line and the control (C) line on the surface of the device. If the CPV antigen exists in the sample, it binds to the gold-conjugated CPV antibody. The antigen-antibody complex moves through the membrane by capillary force and responds to the CPV antibody on the test line, resulting in a red line. The control line indicates that the test is performed correctly and should appear when the test is complete.
The highly selective and sensitive monoclonal antibody to CPV is used as a capture and detector in the kit. The CPV Ag Test Kit can detect CPV antigen in canine feces with high accuracy.