1. INTENDED USE

The Veterinary Rabies Antibody Rapid Test is a fluorescence-based immunoassay designed for:

• Quantitative detection of rabies virus neutralizing antibodies in serum/plasma from vaccinated dogs, cats, and ferrets
• Compliance testing for international pet travel requirements (OIE-standard)
• Vaccination efficacy monitoring (post-vaccination titer evaluation)
• Seroconversion assessment in rabies-exposed animals

Regulatory Status: Complies with WHO/OIE standards (≥0.5 IU/mL threshold)

2. TEST PRINCIPLE

Using competitive fluorescence quenching technology:

1. Reaction: Sample antibodies compete with fluorescein-labeled rabies glycoprotein for binding to immobilized rabies virus antigens
2. Signal Generation: Bound fluorescent conjugates produce signal inversely proportional to antibody concentration
3. Detection:
   • Excitation: 485nm
   • Emission: 525nm
   • Quantitative range: 0.1-10 IU/mL
   • Time-to-result: 15 minutes

Key Features:
✔️ 98.7% correlation with FAVN (Fluorescent Antibody Virus Neutralization)
✔️ No cross-reactivity with other Lyssavirus antibodies
✔️ Stable at 2-30°C (no cold chain required)

Note: Not for human diagnostic use. Confirm positive results with reference lab testing when required by local regulations.

Includes integrated control line for validation. Calibrated against WHO Standard Serum.